Prostate cancer : biology, genetics, and the new therapeutics /
Progress in sequencing and characterizing the human genome has transformed cancer genetics both conceptually and methodologically. In Prostate Cancer: Biology, Genetics, and the New Therapeutics, leading cancer biologists and clinical researchers comprehensively review the latest basic research and...
Other Authors: | , , |
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Format: | Book |
Language: | English |
Published: |
Totowa, N.J. :
Humana Press,
2001
Totowa, N.J. : c2001 Totowa, N.J. : 2001 |
Series: | Contemporary cancer research
Contemporary cancer research |
Subjects: |
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245 | 0 | 0 | |a Prostate cancer : |b biology, genetics, and the new therapeutics / |c edited by Leland W.K. Chung, William B. Isaacs, Jonathan W. Simons |
260 | |a Totowa, N.J. : |b Humana Press, |c 2001 | ||
260 | |a Totowa, N.J. : |b Humana Press, |c c2001 | ||
264 | 1 | |a Totowa, N.J. : |b Humana Press, |c 2001 | |
300 | |a xviii, 531 p. : |b ill. ; |c 26 cm | ||
300 | |a xviii, 531 pages : |b illustrations, portraits ; |c 26 cm | ||
336 | |a text |b txt |2 rdacontent | ||
337 | |a unmediated |b n |2 rdamedia | ||
338 | |a volume |b nc |2 rdacarrier | ||
440 | 0 | |a Contemporary cancer research | |
490 | 1 | |a Contemporary cancer research | |
500 | |a This WorldCat-derived record is shareable under Open Data Commons ODC-BY, with attribution to OCLC |5 CTY | ||
504 | |a Includes bibliographical references and index | ||
505 | 0 | 0 | |t Donald S. Coffey -- |g 1 |t Building the Road to Defeat Prostate Cancer: A Dedication to Donald S. Coffey / |r W. Steven Ward -- |g 2. |t Hereditary Prostate Cancer / |r William B. Isaacs, Jianfeng Xu and Patrick C. Walsh -- |g 3. |t AR Gene Alterations in Prostate Cancer Progression / |r Tapio Visakorpi -- |g 4. |t Lethal Metastatic Human Prostate Cancer: Autopsy Studies and Characteristics of Metastases / |r G. Steven Bova, Kirk M. Chan-Tack and William W. LeCates -- |g 5. |t Tumor Suppressor Genes in Prostate Cancer / |r Robert Bookstein -- |g 6. |t Androgen Receptor Polymorphisms and Prostate Cancer Risk / |r Phillip G. Febbo and Philip W. Kantoff -- |g 7. |t The Genetic Epidemiology of Prostate Cancer: Closing in on a Complex Disease / |r Ronald K. Ross, Juergen K. V. Reichardt and Sue Ann Ingles / |r [et al.] -- |g 8. |t Determination of Gene and Chromosome Dosage in Prostatic Intraepithelial Neoplasia and Prostatic Carcinoma by Molecular Cytogenetic Techniques / |r Junqi Qian and Robert B. Jenkins -- |g 9. |t Genetic Alterations in Prostatic Intraepithelial Neoplasia (PIN) / |r Paul H. Duray, David K. Ornstein and Cathy D. Vocke / |r [et al.] -- |g 10. |t Xenograft Models and the Molecular Biology of Human Prostate Cancer / |r Robert E. Reiter and Charles L. Sawyers -- |g 11. |t Comprehensive Analyses of Prostate Gene Expression / |r Peter S. Nelson -- |g 12. |t The Role of Nuclear Matrix and Cytoskeleton in Cancer / |r Robert H. Getzenberg -- |g 13. |t The Role of Cell Adhesion Molecules in Prostate Development and Carcinogenesis / |r Jer-Tsong Hsieh -- |g 14. |t Ligand Dependent and Independent Activation of the Androgen Receptor / |r Gloria R. Mora and Donald J. Tindall -- |g 15. |t Tyrosine Kinases and Cellular Signaling in Prostate Cancer / |r Hsing-Jien Kung, Clifford G. Tepper and Ralph W. deVere White -- |g 16. |t Molecular Pathways Underlying Prostate Cancer Progression: The Role of Caveolin-1 / |r Timothy C. Thompson, Terry L. Timme and Likun Li / |r [et al.] -- |g 17. |t Angiogenesis and Prostate Cancer / |r Ingrid B. J. K. Joseph and John T. Isaacs -- |g 18. |t Prostate Specific Membrane Antigen / |r Denise S. O'Keefe, Dean J. Bacich and Warren W. D. Heston -- |g 19. |t Targeting Antiapoptotic Genes Upregulated by Androgen Withdrawal Using Antisense Oligodeoxynucleotides to Enhance Androgen- and Chemo-sensitivity in Prostate Cancer / |r Martin E. Gleave, Hideaki Miyake and Colleen Nelson / |r [et al.] -- |g 20. |t Stromal-Epithelial Interaction: From Bench to Bedside / |r Leland W. K. Chung and Haiyen E. Zhau -- |g 21. |t Chemoprevention of Prostate Cancer / |r James D. Brooks and William G. Nelson -- |g 22. |t Anatomic Radical Retropubic Prostatectomy for Prostate Cancer / |r Misop Han and Alan W. Partin -- |g 23. |t Radiation Therapy as Applied to Prostate Cancer: Clinical, Technical, and Biologic Considerations / |r Naren R. Ramakrishna and Theodore L. DeWeese -- |g 24. |t Prostate Cancer Chemotherapy: Closing Out a Century and Opening a New One / |r Jeffrey M. Kamradt and Kenneth J. Pienta -- |g 25. |t The Role of Small Bioactive Peptide and Cell Surface Peptidases in Androgen Independent Prostate Cancer / |r Joel B. Nelson -- |g 26. |t Development of Dendritic Cell-Based Prostate Cancer Vaccine / |r Benjamin A. Tjoa and Gerald P. Murphy -- |g 27. |t Antiprogression Agents for Prostate Cancer / |r Hadley M. Wood and Michael A. Carducci -- |g 28. |t Human Gene Therapy for Urological Oncology / |r Fernando Ferrer, Jonathan W. Simons and Ronald Rodriguez -- |g 29. |t Chemoprevention Trials for Prostate Cancer / |r Peter Greenwald and Ronald Lieberman. |
505 | 0 | 0 | |t Donald S. Coffey -- |t Building the Road to Defeat Prostate Cancer: A Dedication to Donald S. Coffey / |r W. Steven Ward -- |t Cancer Genetics -- |t Hereditary Prostate Cancer / |r William B. Isaacs, Jianfeng Xu, Patrick C. Walsh -- |t AR Gene Alterations in Prostate Cancer Progression / |r Tapio Visakorpi -- |t Lethal Metastatic Human Prostate Cancer: Autopsy Studies and Characteristics of Metastases / |r G. Steven Bova, Kirk M. Chan-Tack, William W. LeCates -- |t Tumor Suppressor Genes in Prostate Cancer / |r Robert Bookstein -- |t Androgen Receptor Polymorphisms and Prostate Cancer Risk / |r Phillip G. Febbo, Philip W. Kantoff -- |t The Genetic Epidemiology of Prostate Cancer: Closing in on a Complex Disease / |r Ronald K. Ross, Juergen K. V. Reichardt, Sue Ann Ingles, Gerhard A. Coetzee -- |t Determination of Gene and Chromosome Dosage in Prostatic Intraepithelial Neoplasia and Prostatic Carcinoma by Molecular Cytogenetic Techniques / |r Junqi Qian, Robert B. Jenkins -- |t Genetic Alterations in Prostatic Intraepithelial Neoplasia (PIN) / |r Paul H. Duray, David K. Ornstein, Cathy D. Vocke, Stephen M. Hewitt, Kristina A. Cole, John W. Gillespie, Chad R. Englert, Emanuel F. Petricoin, David B. Krizman, W. Marston Linehan, Michael R. Emmert-Buck -- |t Xenograft Models and the Molecular Biology of Human Prostate Cancer / |r Robert E. Reiter, Charles L. Sawyers -- |t Comprehensive Analyses of Prostate Gene Expression / |r Peter S. Nelson -- |t Cancer Biology -- |t The Role of Nuclear Matrix and Cytoskeleton in Cancer / |r Robert H. Getzenberg |
505 | 8 | 0 | |t The Role of Cell Adhesion Molecules in Prostate Development and Carcinogenesis / |r Jer-Tsong Hsieh -- |t Ligand Dependent and Independent Activation of the Androgen Receptor / |r Gloria R. Mora, Donald J. Tindall -- |t Tyrosine Kinases and Cellular Signaling in Prostate Cancer / |r Hsing-Jien Kung, Clifford G. Tepper, Ralph W. deVere White -- |t Molecular Pathways Underlying Prostate Cancer Progression: The Role of Caveolin-1 / |r Timothy C. Thompson, Terry L. Timme, Likun Li, Chengzen Ren, Alexei Goltsov, Salahaldin Tahir, Guang Yang -- |t Angiogenesis and Prostate Cancer / |r Ingrid B. J. K. Joseph, John T. Isaacs -- |t Prostate Specific Membrane Antigen / |r Denise S. O'Keefe, Dean J. Bacich, Warren W. D. Heston -- |t Targeting Antiapoptotic Genes Upregulated by Androgen Withdrawal Using Antisense Oligodeoxynucleotides to Enhance Androgen- and Chemo-Sensitivity in Prostate Cancer / |r Martin E. Gleave, Hideaki Miyake, Colleen Nelson, Paul Rennie, Simon Leung -- |t Stromal-Epithelial Interaction: From Bench to Bedside / |r Leland W. K. Chung, Haiyen E. Zhau -- |t Cancer Therapeutics -- |t Chemoprevention of Prostate Cancer / |r James D. Brooks, William G. Nelson -- |t Anatomic Radical Retropubic Prostatectomy for Prostate Cancer / |r Misop Han, Alan W. Partin -- |t Radiation Therapy as Applied to Prostate Cancer: Clinical, Technical, and Biologic Considerations / |r Naren R. Ramakrishna, Theodore L. DeWeese -- |t Prostate Cancer Chemotherapy: Closing Out a Century and Opening a New One / |r Jeffrey M. Kamradt, Kenneth J. Pienta |
505 | 8 | 0 | |t The Role of Small Bioactive Peptides and Cell Surface Peptidases in Androgen Independent Prostate Cancer / |r Joel B. Nelson -- |t Development of Dendritic Cell-Based Prostate Cancer Vaccine / |r Benjamin A. Tjoa, Gerald P. Murphy -- |t Antiprogression Agents for Prostate Cancer / |r Hadley M. Wood, Michael A. Carducci -- |t Human Gene Therapy for Urological Oncology / |r Fernando Ferrer, Jonathan W. Simons, Ronald Rodriguez -- |t Chemoprevention Trials for Prostate Cancer / |r Peter Greenwald, Ronald Lieberman |
520 | |a Progress in sequencing and characterizing the human genome has transformed cancer genetics both conceptually and methodologically. In Prostate Cancer: Biology, Genetics, and the New Therapeutics, leading cancer biologists and clinical researchers comprehensively review the latest basic research and its translational significance for the molecular biology and genetics of prostate cancer, as well as its application in developing novel therapeutics. Highlights of recent molecular genetics research include new light on inactivated tumor suppressor genes, HPC families, the role of the androgen receptor, the progression of prostate cancer, and promising results from transcriptome profiling and proteomics. Research into the basic biology and regulatory mechanisms controlling prostate cancer growth, progression, and stromal-epithelial interaction has revealed many new possibilities for therapeutic intervention, including cell adhesion molecules, the androgen receptor, use of the nuclear matrix, Caveolin-1, and the prostate-specific membrane antigen. Among the cancer therapeutic modalities discussed are chemoprevention, radiotherapy, radical retropubic prostatectomy, the development of dendritic-cell based vaccines, differentiation therapies, and gene therapy. Comprehensive and cutting-edge, Prostate Cancer: Biology, Genetics, and the New Therapeutics synthesizes all the major recent work that is not only rapidly unraveling the mysteries of prostate cancer, but also dramatically improving today's therapeutic approaches | ||
561 | 1 | |a From the Boston Medical Library |8 222086361150003941 | |
650 | 0 | |a Prostate |x Cancer |x Genetic aspects | |
650 | 0 | |a Prostate |x Cancer |x Treatment | |
650 | 0 | |a Prostate |x Cancer | |
650 | 2 | |a Prostatic Neoplasms | |
650 | 7 | |a Prostate |x Cancer |2 fast | |
650 | 7 | |a Prostate |x Cancer |x Genetic aspects |2 fast | |
650 | 7 | |a Prostate |x Cancer |x Treatment |2 fast | |
650 | 1 | 2 | |a Prostatic Neoplasms |x genetics |
650 | 2 | 2 | |a Prostatic Neoplasms |x pathology |
650 | 2 | 2 | |a Prostatic Neoplasms |x therapy |
700 | 1 | |a Chung, Leland W. K |0 http://viaf.org/viaf/74032639 | |
700 | 1 | |a Chung, Leland W. K |1 http://viaf.org/viaf/74032639 | |
700 | 1 | |a Chung, Leland W. K | |
700 | 1 | |a Isaacs, William Brewster |0 http://viaf.org/viaf/49403564 | |
700 | 1 | |a Isaacs, William Brewster |1 http://viaf.org/viaf/49403564 | |
700 | 1 | |a Isaacs, William Brewster | |
700 | 1 | |a Simons, Jonathan W |0 http://viaf.org/viaf/54327649 | |
700 | 1 | |a Simons, Jonathan W |1 http://viaf.org/viaf/54327649 | |
700 | 1 | |a Simons, Jonathan W | |
776 | 0 | 8 | |i Online version: |t Prostate cancer |d Totowa, N.J. : Humana Press, ©2001 |w (OCoLC)606509963 |
776 | 0 | 8 | |i Online version: |t Prostate cancer |d Totowa, N.J. : Humana Press, ©2001 |w (OCoLC)630439479 |
830 | 0 | |a Contemporary cancer research | |
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