Endocrinology of the lung : development and surfactant synthesis /
During the past thirty years, great progress has been made in defining the roles of steroid, peptide, and polypeptide hormones in the processes of lung morphogenesis, differentiation of specialized cell types, and surfactant synthesis. In Endocrinology of the Lung, Carole Mendelson has assembled a p...
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| Format: | Book |
| Language: | English |
| Published: |
Totowa, N.J. :
Humana Press,
©2000
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| Series: | Contemporary endocrinology (Totowa, N.J.)
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| Subjects: |
| Summary: | During the past thirty years, great progress has been made in defining the roles of steroid, peptide, and polypeptide hormones in the processes of lung morphogenesis, differentiation of specialized cell types, and surfactant synthesis. In Endocrinology of the Lung, Carole Mendelson has assembled a panel of leading investigators to critically review the roles of various classes of endocrine, paracrine, and neuroendocrine factors in the regulation of lung development and surfactant production. Special attention is accorded the actions of glucocorticoids in lung branching morphogenesis and the synthesis of surfactant glycerophospholipids and proteins. Also extensively examined are the roles of cell-cell interactions and the elaboration of various growth factors and bioactive peptides in pulmonary cell differentiation, gene expression, and pathophysiology. The model systems utilized in these studies range from whole animal to transgenic and gene-targeted mice, to organ and cell culture. State-of-the-art and comprehensive, Endocrinology of the Lung constitutes a powerful new standard guide that illuminates the complex endocrinology of the lung for investigators actively studying hormone action in pulmonary biology and medicine today |
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| Physical Description: | 1 online resource (x, 344 pages) : illustrations |
| Format: | Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. |
| Bibliography: | Includes bibliographical references and index |
| ISBN: | 1468496085 1592590144 9781468496086 9781592590148 |