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020 |a 159259963X  |q ebook 
020 |a 9781588292025  |q alkaline paper 
020 |a 9781592599639  |q ebook 
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060 1 0 |a QZ 50  |b P9573 2006 
082 0 0 |a 616/.042  |2 22 
096 |a QZ50  |b P932 2006 
245 0 0 |a Principles of molecular medicine /  |c edited by Marschall S. Runge, Cam Patterson ; foreword by Victor A. McKusci ; section editors, Richard C. Boucher ... [et al.] 
250 |a 2nd ed 
260 |a Totowa, N.J. :  |b Humana Press,  |c c2006 
300 |a xxv, 1268 p., [8] p. of plates :  |b ill. (some col.), col. map, ports. ;  |c 29 cm 
336 |a text  |b txt  |2 rdacontent 
337 |a unmediated  |b n  |2 rdamedia 
338 |a volume  |b nc  |2 rdacarrier 
504 |a Includes bibliographical references and index 
505 0 |a Axonal regeneration and recovery from chronic central nervous system injury / Stephen M. Strittmatter -- XIV. Psychiatry / Kerry J. Ressler and Charles B. Nemeroff. Molecular mechanisms regulating behavior: focus on genetic and environmental influences / Kerry J. Ressler and Charles B. Nemeroff -- The complex genetics of psychiatric disorders / Ming T. Tsuang, Stephen J. Glatt, and Stephen V. Faraone -- Treating depression: antidepressant-activated signaling pathways as a source for novel drug targets / Marcelo Pa��ez-Pereda and Florian Holsboer -- Anxiety disorders / Gregory M. Sullivan and Jack M. Gorman -- Trauma spectrum disorders / christine Heim, J. Douglas Bremner, and Charles B. Nemeroff -- Schizophrenia / Carol A. Tamminga, Deborah C. Medoff, and Gunvant Thaker -- Disorders of substance abuse and dependence / Eric J. Nestler and Jennifer Chao -- Autism and related disorders / Linmarie Sikich ... [et al.] 
505 0 |a Cardiac hypertrophy / Thomas force and Jeffrey D. Molkentin -- Arrhythmias / Barry London -- Genomics / Calum A. MacRae and Christopher J. O'Donnell -- Cardiovascular gene therapy / David A. Dichek -- III. Pulmonary diseases / Richard C. Boucher and Pedar G. Noone. Idiopathic interstitial pneumonias / Talmadge E. King, Jr. -- Asthma / Stephen T. Holgate, Gordon Dent, and Mark G. Buckley -- Pulmonary emphysema / Steven D. Shapiro -- Pulmonary hypertension / Brian Fouty and David M. Rodman -- Acute lung injury / David C. Christiani and Michelle Ng Gong -- Primary ciliary dyskinesia / Peadar G. Noone, Maimoona Zariwala, and Michael R. Knowles -- Cystic fibrosis / Scott H. Donaldson and Richard C. Boucher -- Gene therapy for lung diseases / Jane C. Davies, Duncan M. Geddes, and Eric W.F.W. Alton -- Sarcoidosis / Kelly D. Chason and Stephen L. Tilley -- Disorders of pulmonary surfactant homeostasis / Jeffrey A. Whitsett, Susan E. Wert, and Bruce C. Trapnell -- IV. Endocrinology / Michael J. McPhaul. Mechanisms of hormone action / Stephen R. Hammes, Carol A. Lange, and Michael J. McPaul -- Diabetes mellitus / William L. Lowe, Jr. -- Pituitary function and neoplasia / Shlomo Melmed-- Growth hormone deficiency disorders / Amy Potter and John A. Phillips, III -- 
505 0 |a I. Genetics / Terry Magnuson and James P. Evans. Mendelian inheritance / Bruce R. Korf -- Nontraditional inheritance / Shawn E. McCandless and Suzanne B. Cassidy -- Identifying causal genetic factors / Christopher I. Amos, John S. Witte, and William G. Neuman -- Cancer genetics and molecular oncology / Sharon E. Plon -- Pharmacogenetics / Renee E. Edkins and Dennis J. Cheek -- Hemophilia as a model disease for gene therapy of genetic disorders / Jay Lozier -- Genetic counseling / Robin L. Bennett -- Animal models in biomedical research: ethics, challenges, and opportunities / Robert W. Williams -- Ethical, legal, and social implications / Marcia Van Riper -- II. Cardiology / Anthony Rosenzweig. Congenital heart disease / Lazaros K. Kochilas and Alvin J. Chin -- Inherited cardiomyopathies / Carolyn Y. Ho and Christine E. Seidman -- -- Heart failure: emerging concepts in excitation-contraction coupling and [beta]-adrenoceptor coupling / Clive J. Lewis ... [et al.] -- Aortic diseases / Saumya Das, James L. Januzzi, Jr., and Eric M. Isselbacher -- Atherosclerotic coronary disease / Robert e. Gerszten and Antony Rosenzweig -- Lipid metabolism and coronary artery disease / Mason W. Freeman -- Hypertension / Khurshed A. Katki and Donald J. DiPette -- 
505 0 |a Multiple myeloma: a story of genes and the environment / Kenneth H. Shain and William S. Dalton -- HIV-1, AIDS, and related malignancies / Maureen M. Goodenow and James J. Kohler -- X. Hematology / Swee Lay Thein. Disorders of the red cell membrane / Jean Delaunay and Gordon W. Stewart -- Paroxysmal nocturnal hemoglobinuria / Bruno Rotoli, Khedoudja Nafa, and Antonio M. Risitano -- Iron metabolism / Nancy C. Andrews -- Correction of genetic blood defects by gene transfer / Marina Cavazzana-Calvo ... [et al.] -- Bone marrow failures syndromes / J. Eric Turner and Thomas C. Shea -- Coagulation disorders / Stephan Moll and Gilbert C. White II -- Advances in transfusion safety / Lorna M. Williamson and Jean-Pierre Allain -- XI. Immunology and infectious diseases / Steven M. Holland. Immunomodulation / Juan C. Gea-Banacloche -- HIV molecular biology, treatment, and resistance / Frank Maldarelli -- Cellular and molecular aspects of pneumonia / Marcus J. Schultz and Tom van der Poll -- Molecular pathogenesis of fungal infections / Brahm H. Segal -- XII. Dermatology / Luis A. Diaz and Lowell A. Goldsmith. Psoriasis / James T. Elder -- Atopic dermatitis / Kefei Kang, Donald Y.M. Leung, and Kevin D. Cooper -- 
505 0 |a Pemphigus foliaceus, pemphigus vulgaris, paraneoplastic pemphigus, bullous pemphigoid, herpes gestationis and cicatricial pemphigoid / Ning Li ... [et al.] -- Systemic lupus erythematosus / Amr H. Sawalha, Luis A. Diaz, and John B. Harley -- Systemic sclerosis / Chris T. Derk and Sergio A. Jimenez -- Diseases with signaling and transcriptional abnormalities / David S. Rubenstein, Amy Stein, and Lowell A. Goldsmith -- Genetic skin diseases with neoplasia / David S. Rubenstein -- Melanoma and nevi / Nancy E. Thomas -- Disorders of hypopigmentation / Julie V. Schaffer and Jean L. Bolognia -- Epidermolysis bullosa / Jouni Uitto, Gabriele Richard, and Angela M. Christiano -- Connective tissue disorders: the paradigms of Ehlers-Danlos syndrome and pseudoxanthoma elasticum / Jouni Uitto and Franziska Ringpfeil -- Genetic epidermal diseases / Amy Stein and Lowell A. Goldsmith -- Genetic hair and nail defects / Marija Tadin-Strapps and Angela M. Christiano -- Metabolic genetic disorders with prominent skin findings / Christopher B. Mizelle and Lowell A. Goldsmith -- Heritable conditions affecting tissues of the oral cavity / J. Tim Wright -- 
505 0 |a Skeletal muscle structure and function / Elizabeth M. McNally, Karen A. Lapidos, and Matthew T. Wheeler -- Stem cells and muscle regeneration / Cindy M. Martin, Thomas J. Hawke, and Daniel J. Garry -- Skeletal muscle hypertrophy and response to training / Zhen Yan and R. Sanders Williams -- Muscular dystrophies: mechanisms / Peter B. Kang and Louis M. Kunkel -- Rhabdomyosarcomas / Stephen J. Tapscott -- IX. Oncology / W. Stratford May, Jr. Apoptosis / W. Stratford May, Jr. and Xingming Deng -- Colorectal cancer / Satya Narayan -- Breast cancer / Yi Huang and Nancy E. Davidson -- Lung cancer / Lei Xiao -- Discoveries and frontiers in prostate cancer translational sciences / Jonathan W. Simons -- Cutaneous melanoma / Moira R. Jackson and Stephen P. Sugrue -- Applications of gene expression profiling to the study of malignant gliomas / Anthony T. Yachnis and Henry V. Baker -- Acute myeloid leukemias / Iris T. Chan and D. Gary Gilliland -- Acute lymphoblastic leukemia / Alexander E. Perl and Donald Small -- Chronic myelogenous leukemia / Brian J. Druker -- Non-Hodgkin's lymphoma and chronic lymphocytic leukemia / Ayad M. Al-Katib and Anwar N. Mohamed -- 
505 0 |a Thyroid disorders / Peter Kopp -- Disorders of the parathyroid gland / Andrew Arnold and Michael A. Levine -- Congenital adrenal hyperplasia / Robert C. Wilson and Maria I. New -- Adrenal diseases / Richard J. Auchus, William E. Rainey, and Keith L. Parker -- Multiple endocrine neoplasia type 1 / Rajesh V. Thakker -- Multiple endocrine neoplasia type 2 / Robert F. Gagel ... [et al.] -- Disorders of sex determination and differentiation / Charmian A. Quigley -- Sex chromosome disorders / Andrew R. Zinn -- Disorders of pubertal development / Tomonobu Hasegawa -- Defects of androgen action / Michael J. McPaul -- Molecular endocrinology of the testis / Marco Marcelli ... [et al.] -- Ovarian diseases / Elizabeth M. McGee and Tammy L. Loucks -- V. Metabolic disorders / Samuel Klein. Gastrointestinal regulation of food intake / Patrick Tso and Min Liu -- Cellular regulation of lipolysis / Allan Green -- Fat-induced insulin resistance and atherosclerosis / Guenther Boden -- Metabolic and molecular aspects of sarcopenia / W. Todd Cade and Kevin E. Yarasheski -- Adipose tissue development and metabolism / Sheila Collins, Yushi Bai, and Jacques Robidoux -- 
505 0 |a VI. Gastroenterology / David A. Brenner. Hepatitis C / Johnson Yiu-Nam Lau ... [et al.] -- Molecular diagnostics in hepatitis B / Scott Bowden and Stehen Locarnini -- Hereditary hemochromatosis / francesca Ferrara, Elena Corradini, and Antonello Pietrangelo -- Pancreatic exocrine dysfunction / David C. Whitcomb and Jonathan A. Cohn -- Small and large bowel dysfunction / Deborah C. Rubin -- the molecular mechanisms of Helicobacter pylori-associated gastroduodenal disease / Peter B. Ernst -- VII. Nephrology / William E. Mitch. Nitric oxide synthase and cyclooxygenase in the kidneys / Christopher S. Wilcox -- Hypertension and socium channel turnover / Douglas C. Eaton, Bela Malik, and He-Ping Ma -- Nephrogenic diabetes insipidus: water and urea transport / Jeff M. sands and Daniel G. Bichet -- Glomerulonephritis and smad signaling / Hui Y. Lan and Richard J. Johnson -- Interstiial nephritis / Carla Zoja and Giuseppe Remuzzi -- The pathophysiology of acute renal failure / Didier Portilla ... [et al.] -- Loss of lean body mass in uremia / S. Russ Price and William E. Mitch -- Mechanisms of renal allograft rejection / Daniel R. Goldstein, Anirban Bose, and Fadi G. Lakkis -- VIII. Musculoskeletal / Daniel J. Garry. Muscle development and differentiation / Eric N. Olson -- 
505 0 |a XII. Neurology / Stephen M. Strittmatter. The genetic basis of human cerebral cortical malformations / Bernard S. Chang and Christopher A. Walsh -- Muscular dystrophies: molecular diagnosis / Eric P. Hoffman and Erynn S. Gordon -- Channelopathies of the nervous system / Stephen C. Cannon -- Charcot-Marie-tooth disease and related peripheral neuropathies / James R. Lupski -- Amyotrophic lateral sclerosis and related motor neuron disorders: lessons in pathogenesis and therapy from genetics / Robert H. Brown, Jr. -- Trinucleotide repeat disorders / Huda Y. Zoghbi -- Parkinson's disease / Deepak M. Sampathu and Virginia M.-Y. Lee -- Genetics and neurobiology of Alzheimer's disease and frontotemporal dementias / Peter H. St. George-Hyslop -- Prion diseases / Adriano Aguzzi -- Narcolepsy and other neurological sleep disorders / Thomas E. Scammell -- Neurofibromatosis 1 and 2 / Gregory J. Esper and David H. Gutmann -- 
650 0 |a Medical genetics 
650 0 |a Molecular biology 
650 0 |a Pathology, Molecular 
650 4 |a Medicina gene��tica 
650 6 |a Biologie mole��culaire 
650 6 |a Ge��ne��tique me��dicale 
650 6 |a Pathologie mole��culaire 
650 7 |a Gene��tica molecular  |2 larpcal 
650 1 2 |a Genetics, Medical 
650 2 2 |a Genetic Therapy 
650 2 2 |a Molecular Biology 
700 1 |a Patterson, Cam 
700 1 |a Runge, Marschall Stevens,  |d 1954- 
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