Asymmetric synthesis of natural products /
Asymmetric Synthesis of Natural Products Ari Koskinen Department of Chemistry, University of Oulu, Finland Natural product synthesis has played a key role in the development of many synthetic methods and will continue to do so in the future. Many recent advances in such diverse fields as immunology,...
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| Format: | Book |
| Language: | English |
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Chichester ; New York :
J. Wiley,
[1993], ©1993
Chichester ; New York : c1993 Chichester ; New York : [1993] |
| Subjects: |
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| 100 | 1 | |a Koskinen, Ari |0 http://viaf.org/viaf/sourceID/LC|n92112366 | |
| 100 | 1 | |a Koskinen, Ari | |
| 245 | 1 | 0 | |a Asymmetric synthesis of natural products / |c Ari Koskinen |
| 260 | |a Chichester ; |a New York : |b J. Wiley, |c [1993], ©1993 | ||
| 260 | |a Chichester ; |a New York : |b J. Wiley, |c c1993 | ||
| 263 | |a 9306 | ||
| 264 | 1 | |a Chichester ; |a New York : |b J. Wiley, |c [1993] | |
| 264 | 4 | |c ©1993 | |
| 300 | |a xiii, 234 p. : |b ill. ; |c 25 cm | ||
| 300 | |a xiii, 234 pages : |b illustrations ; |c 25 cm | ||
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| 500 | |a This WorldCat-derived record is shareable under Open Data Commons ODC-BY, with attribution to OCLC |5 CTY | ||
| 504 | |a Includes bibliographical references and indexes | ||
| 505 | 0 | |a 7.3. Polypropionates: Polyether Antibiotics. 7.4. Aromatic Polyketides -- 8. Isoprenoids. 8.1. Terpenoids. 8.2. Carotenoids. 8.3. Steroids -- 9. Shikimic Acid Derivatives -- 10. Alkaloids. 10.1. Heterocyclic Alkaloids. 10.2. Alkaloids with an Exocyclic Nitrogen. 10.3. Polyamine Alkaloids. 10.4. Peptide Alkaloids. 10.5. Terpene Alkaloids | |
| 505 | 0 | |a Introduction -- Chirality, topology and asymmetric synthesis -- Asymmetric synthesis -- Carbohydrates -- Amino acids, peptides and proteins -- Nucleosides, nucleotides and nucleic acids -- Polyketides -- Isoprenoids -- Carotenoids -- Steroids -- Shikimic acid derivatives -- Alkaloids | |
| 505 | 2 | |a 1. Introduction. 1.1. Some Properties of Natural Products. 1.2. Natural Products as Drugs. 1.3. Structures of Natural Products. 1.4. Synthesis of Natural Products -- 2. Chirality, Topology and Asymmetric Synthesis. 2.1. The Need for Enantiopure Compounds. 2.2. Determination of Enantiomeric Purity. 2.3. Chirality and Thermodynamic Principles of Asymmetric Induction. 2.4. Methods for Obtaining Chiral Compounds -- 3. Asymmetric Synthesis. 3.1. Allylic Strain. 3.2. Reactions of the Carbonyl Group. 3.3. Reactions of Olefins -- 4. Carbohydrates. 4.1. Monosaccharides. 4.2. Polysaccharides. 4.3. Glycoproteins and Proteoglycans. 4.4. Glycolipids. 4.5. Sugar Antibiotics. 4.6. Cyclitols -- 5. Amino Acids, Peptides and Proteins. 5.3. Enzymes and Receptors. 5.4. Clinical Modification of Peptides. 5.5. Biosynthesis of Amino Acids. 5.6. Asymmetric Synthesis of Amino Acids -- 6. Nucleosides, Nucleotides and Nucleic Acids -- 7. Polyketides. 7.1. Biosynthesis. 7.2. Fatty Acids | |
| 520 | |a Asymmetric Synthesis of Natural Products Ari Koskinen Department of Chemistry, University of Oulu, Finland Natural product synthesis has played a key role in the development of many synthetic methods and will continue to do so in the future. Many recent advances in such diverse fields as immunology, cellular biology and materials science have been achieved through the synthetic chemist' s ability to construct often very complicated structures in one enantiomeric form. This book introduces the student to this rapidly growing field of organic chemistry. The first three chapters present the foundations of asymmetric synthesis, with Chapter 3 describing, in concise but clear rationalizations, the reasons for the major asymmetric transformations. Chapters 4 to 10 cover individual classes of natural products; their structures, biosynthesis and interrelationships as well as examples of asymmetric syntheses and the practical value of these compounds | ||
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| 650 | 2 | |a Alkenes |x chemical synthesis | |
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| 650 | 2 | |a Carbohydrates |x chemical synthesis | |
| 650 | 2 | |a Carotenoids |x chemical synthesis | |
| 650 | 2 | |a Chemistry, Organic |x chemical synthesis | |
| 650 | 2 | |a Fatty Acids |x chemical synthesis | |
| 650 | 2 | |a Nucleic Acids |x chemical synthesis | |
| 650 | 2 | |a Nucleosides |x chemical synthesis | |
| 650 | 2 | |a Nucleotides |x chemical synthesis | |
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| 650 | 2 | |a Pharmaceutical Preparations |x chemical synthesis | |
| 650 | 2 | |a Proteins |x chemical synthesis | |
| 650 | 2 | |a Steroids |x chemical synthesis | |
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