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|a TEC072000
|2 bisacsh
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1 |
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|a Helveston, Eugene M.,
|d 1934-
|e author
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| 245 |
1 |
0 |
|a Death to beauty :
|b the transformative history of Botox /
|c Eugene M. Helveston
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| 250 |
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|a First edition
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| 264 |
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1 |
|a Bloomington, Indiana :
|b Indiana University Press Office of Scholarly Publishing,
|c [2024]
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| 264 |
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4 |
|c ©2024
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| 300 |
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|a 1 online resource (216 pages)
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 500 |
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|a Includes index
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| 505 |
0 |
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|a Cover -- Title Page -- Copyright -- Dedication -- Contents -- Author's Note -- Preface -- Acknowledgments -- 1. Clostridium Botulinum -- 2. The World's Deadliest Poison -- 3. The Canning Industry -- 4. An Outbreak in the United States -- 5. A Rare and Deadly Disease -- 6. World War II Sets the Stage -- 7. Camp Detrick-US Army Biological Warfare Laboratories -- 8. Fort Detrick and the CIA -- 9. The Government Steps In -- 10. Edward Schantz Testifies -- 11. Back in Madison -- 12. Dr. Alan B. Scott -- 13. Progress in the Lab -- 14. First Injection in a Primate -- 15. First Injection in a Human -- 16. Joining the Team -- 17. Manufacturing Begins -- 18. Marketing and Selling a New Drug -- 19. Botox and Beauty -- 20. Dermatology Opens the Floodgates -- 21. Botox and Neurology -- 22. The Legacy -- Epilogue -- Appendices -- Glossary -- Notes -- Index -- About the Author
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| 520 |
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|a "In the 1970s, Dr. Alan Scott sought to selectively weaken eye muscles to treat strabismus (when one or both eyes are misaligned) without surgery. After failed attempts with other agents, Scott developed a method to stabilize the bacteria that causes botulism, culminating in a drug that eventually became known as Botox. In Death to Beauty, Eugene M. Helveston, MD, follows the unlikely story of botulism's 1817 discovery in contaminated German sausages, to its use in military and research facilities, to Scott, an ophthalmologist who aimed to safely use the drug in humans. Scott struggled alone as an unknown in the pharmaceutical industry, searching for clinical trial financing and FDA approval, which he achieved at a fraction of the billions big pharma usually spends to bring a drug to market. Eventually, the company Allergan bought him out, capitalizing on the possibilities for cosmetic uses. Scott's formula was renamed "Botox" and reached annual sales in the billions. After the sale, Scott received no further compensation from Botox sales and remained the same unassuming man.A fascinating walk through the intricate history of how the world's deadliest toxin starting as a treatment for crossed eyes became a routine tool for the cosmetic industry, Death to Beauty will make you rethink success, beauty, and deadly bacteria"--
|c Provided by publisher
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| 588 |
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|a Description based on print version record
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| 650 |
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|a Botulinum toxin
|x Therapeutic use
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| 650 |
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|a Dermatologic agents
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| 650 |
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|a Surgery, Plastic
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| 776 |
0 |
8 |
|i Print version:
|a Helveston, Eugene M
|t Death to Beauty
|d Bloomington : Indiana University Press,c2024
|z 9780253067807
|
| 999 |
1 |
0 |
|i 846157ce-7c61-4118-9d28-6100c074c3f5
|l 99119530121208501
|s US-NCD
|m death_to_beautytransformative_history_of_botox_____________________________2024____1__indiaa________________________________________helveston__eugene_m________________e
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