Epi-Informatics : discovery and development of small molecule epigenetic drugs and probes /

Epi-Informatics : discovery and development of small molecule epigenetic drugs and probes /

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Epi-Informatics: Discovery and Development of Small Molecule Epigenetic Drugs and Probes features multidisciplinary strategies with strong computational approaches that have led to the successful discovery and/or optimization of compounds that act as modulators of epigenetic targets. This book is in...

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Bibliographic Details
Other Authors: Medina-Franco, José L. (Editor), Medina-Franco, José L. (Editor)
Format: Book
Language:English
Published: Amsterdam ; Boston : Academic Press/Elsevier, [2016]
Subjects:
Drug development
Epigenetics
Pharmaceutical industry > Technological innovations
Pharmacogenomics
Médicaments > Développement
Pharmacogénomique
Épigénétique
MEDICAL / Pharmacology
MEDICAL > Pharmacology
Electronic books
Table of Contents:
  • Front Cover; Epi-Informatics: Discovery and Development of Small Molecule Epigenetic Drugs and Probes; Copyright; Dedication; Contents; List of Contributors; Preface; 1
  • Introduction of Epigenetic Targets in Drug Discovery and Current Status of Epi-Drugs and Epi-Probes; 1. INTRODUCTION; 1.1 Current Status of Epigenetic Drugs; 1.2 Epigenetics; 1.2.1 DNA Methylation; 1.2.2 Histone Modification; 1.2.3 Noncoding RNAs; 1.3 The Genetics of Epigenetics; 1.4 Epigenomics; 1.5 Conclusions; 1.6 Perspectives; ACKNOWLEDGMENTS; REFERENCES; 2
  • Overview of Computer-Aided Drug Design for Epigenetic Targets

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