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|a 616.99/4075
|2 23
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| 245 |
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|a Biomarkers in cancer screening and early detection /
|c edited by Sudhir Srivastava
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| 264 |
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|a Chichester, West Sussex ;
|a Hoboken, NJ :
|b John Wiley & Sons, Ltd,
|c 2017
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|c ©2017
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| 300 |
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|a 1 online resource (xiv, 304 pages)
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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|g polychrome
|2 rdacc
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| 347 |
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|a text file
|2 rdaft
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| 490 |
1 |
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|a Translational oncology
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| 504 |
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|a Includes bibliographical references and index
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| 505 |
0 |
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|a Nuts and bolts of biomarker research / Sharmistha Ghosh and Sudhir Srivastava -- Cancer genome methylation : biology, biomarker and therapeutic opportunities / Shashwat Sharad, Taduru Sreenath, Shiv Srivastava, and Albert Dobi -- Microrna biomarkers for early detection of cancer / Wendy Wang, Matthew R. Young, and Sudhir Srivastava -- Inflammation and cancer / Pamela L. Beatty, Sandra Cascio, and Olivera J Finn -- Exosomes : a valuable biomedical tool in biomarker discovery and development / Jocelyn Lee, Sharmistha Ghosh, and Sudhir Srivastava -- Epithelial-to-mesenchymal transition (EMT) : clinical implications / Elisa CWoodhouse and Suresh Mohla -- Breast cancer / Benjamin A. Katchman, Christos Patriotis, and Karen S Anderson -- Ovarian cancer / Christos Patriotis, Archana Simmons, Karen H. Lu, Robert C. Bast, Jr, and Steven J. Skates -- Esophageal cancer biomarkers / Yanxin Luo, Kishore Guda, Sanford Markowitz, Amitabh Chak, Andrew M Kaz, and William M Grady -- Predictive biomarkers for therapy in adenocarcinoma of the upper digestive tract / Heath D Skinner, Qiongrong Chen, Elena Elimova, Roopma Wadhwa, Shumei Song, and Jaffer A Ajani -- Pancreatic cancer / Sam CWang and Peter J Allen -- Colon cancer / Paul DWagner -- Prognosis and predictive biomarkers for colorectal cancer / Upender Manne, Balananda-Dhurjati Kumar Putcha, Temesgen Samuel, and Sudhir Srivastava -- Early detection of lung cancer / Mohamed Hassanein, Melinda C. Aldrich, Stephen A. Deppen, Karl E. Krueger, Eric L. Grogan, and Pierre P. Massion -- Commonalities in lung cancer and COPD / Malgorzata Wojtowicz and Eva Szabo -- Prostate cancer / Jacob Kagan, Ian M. Thompson, and Daniel W. Chan -- Improving the clinical validity of biomarker research in cancer detection / David F. Ransohoff -- Cancer overdiagnosis, ramifications and research strategies / Barbara K. Dunn and Barnett S. Kramer -- Predictive markers and driver genes from treatment trials : potential utility for early diagnosis / Brian S. Sorg, Sarfraz Memon, Kelly Y. Kim, Aniruddha Ganguly, Tracy Lively, James Tricoli, Magdalena Thurin, Lokesh Agrawal, Tawnya C. McKee, Barbara A. Conley, and J. Milburn Jessup -- Statistical consideration in predictive and prognostic markers / Fei Ye and Yu Shyr -- Clinical validation of molecular biomarkers in translational medicine / Harry B. Burke and William E. Grizzle -- Cancer biomarker assays : performance standards / Anna K Fuzery and Daniel W. Chan -- Bioethics and cancer biomarker research / Nathan Nobis, William Grizzle, and Stephen Sodeke -- Colon cancer screening / Molly Perencevich, Jennifer Inra, and Sapna Syngal
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| 506 |
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|a Restricted for use by site license
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| 520 |
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|a Biomarkers in Cancer Screening and Early Detection offers a comprehensive, state-of-the-art perspective on the various research and clinical aspects of cancer biomarkers, from their discovery and development to their validation, clinical utility, and clinical use. The primary purpose of this book is to summarize and present best practices in this field to date, and offer actionable information - and hopefully also inspiration - to move discovery and clinical application forward. This latest volume of the Translational Oncology series, Biomarkers in Cancer Screening and Early Detection is organized into three sections: Section I lays the foundation for biomarker discovery, development and validation. Section II presents organ-specific topics relevant to the clinical needs in early detection, the natural history of the disease and associated evidence in support of biomarker research, an overview of the current state-of-the art in biomarker research, current progress toward bringing these biomarkers into clinical use and the future of biomarker-based screening and early detection for the respective organ type. Finally, Section III offers chapters that address the current screening strategies for selected organ types, discusses deficiencies with the present practice and identifies clinical needs that may benefit from biomarker-based approaches. This latest volume of the Translational Oncology series, Biomarkers in Cancer Screening and Early Detection: Provides immediately actionable information - and hopefully also inspiration - to move discovery and clinical application forward, Considers the cutting edge "bench to bedside and back" breakthroughs which have transformed the diagnosis, prognosis and treatment of cancer, Discusses screening guidelines, research strategies, and issues surrounding cancer overdiagnosis, Offers vital knowledge to help develop personalized cancer treatment for individual patients with specific cancers, The development of cancer is preceded by numerous mutations and changes which transform normal cells into benign tumors, and progressively into malignant and metastatic forms. This enormous complexity makes cancer detection, diagnosis, and treatment challenging and therefore the ability to identify tumors that are destined to progress at an early stage will allow effective treatment interventions and reduce deaths. This new book comprehensively summarises the current state of the field and is an ideal resource for clinical and research oncologists interested in the progress of screening and detection of cancer. Book jacket
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| 533 |
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|a Electronic reproduction
|b Ann Arbor, MI
|n Available via World Wide Web.
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| 588 |
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|a Description based on online resource; title from digital title page (viewed on July 27, 2017)
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| 650 |
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|a Tumor markers
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| 650 |
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2 |
|a Biomarkers, Tumor
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| 650 |
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2 |
|a Early Detection of Cancer
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| 650 |
|
7 |
|a Tumor markers
|2 fast
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| 700 |
1 |
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|a Srivastava, Sudhir,
|d 1954-
|e editor
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| 710 |
2 |
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|a ProQuest ebook central
|p Education 2017
|
| 776 |
0 |
8 |
|i Print version:
|t Biomarkers in cancer screening and early detection
|d Chichester, West Sussex ; Hoboken, NJ : John Wiley & Sons, Ltd, 2017
|z 9781118468807
|w (DLC) 2017022050
|
| 830 |
|
0 |
|a Translational oncology (Series)
|
| 999 |
1 |
0 |
|i 2da7727e-2d72-4f53-951b-ec339908e1a6
|l 9977137025703681
|s US-PU
|m biomarkers_in_cancer_screening_and_early_detection_________________________2017_______johnwa___________________________________________________________________________e
|